陈丹萍简介
陈丹萍,女,1989年7月,中山大学博士学位,贵州大学校聘副教授,药物分析方向,硕士研究生导师。
邮箱:330886736@qq.com
2007年9月-2011年6月, 贵州大学,化学与化工学院, 学士
2011年9月-2014年6月,贵州大学,精化中心, 硕士
2015年9月-2019年1月, 中山大学, 化学学院, 博士
2020年5月至今,贵州大学,学院,校聘副教授
【学术兼职及荣誉称号】
贵州省药学会药物化学专业委员会委员
获得2022年学院青年教师比赛二等奖
贵州省普通高等学校青年科技人才
【主持项目】
1.2021.04.01—2023.12.31,贵州省科技基础研究计划项目,基于核酸等温扩增的DNA 主动去甲基化过程 Tet 蛋白的氧化作用方式研究(主持,在研);
2. 2021.12.31—2024.12.30,贵州省普通高等学校青年科技人才成长项目,基于滚环等温扩增信号放大策略的N6-甲基腺嘌呤研究(主持,在研);
3.2021.01.01—2023.12.31,贵州大学引进人才科研项目,基于能量共振转移信号放大技术的 DNA 去甲基化中间体研究,(主持,在研);
4.2021.01.01—2023.12.31,贵州大学培育项目,(主持,在研);
【近期发表论文】
1. Danping Chen, Yang Wang, Mingming Mo, Junjie Zhang, Yanfei Zhang,YuzhiXu, Si-Yang Liu, Jun Chen, Yingjun Ma, Li Zhang, Zong Dai*. Polymerization retardation isothermal amplification(PRIA): a strategy enables sensitively quantify genome-wide 5-methylcytosine oxides rapidly on handy instruments with nanoscale sample input. Nucleic Acids Res. 2019, 47, e119.(IF=16.97)
2. Danping Chen, Yang Wang, Jun Chen, Yanfei Zhang, Zong Dai*, Xiaoyong Zou. Polymerization retardation isothermal amplification strategy enables the sensitive and facile investigation of the flanking sequence preference of ten-eleven translocation 2 protein. Anal. Chim. Acta. 2020, 1109, 140-147.(IF=6.55)
3. Jun Chen, Yanfei Zhang, Danping Chen, Tianchen Wang, Wen Yin, Hui-Hui Yang, Yuzhi Xu, Jin-Xiang Chen, Zong Dai*, Xiaoyong Zou. Toehold-mediated ligation-free rolling circle amplification enables sensitive and rapid imaging of messenger RNAsinsitu in cells . Anal. Chim. Acta. 2021, 1160, 338463.
4. Lihui Shao, Sili Fan, Yingfen Meng, Yiyuan Gan, Wubin Shao, Zhenchao Wang*, Danping Chen*, Guiping Ouyang*. Design, synthesis, biological activities and 3D-QSAR studies of quinazolinone derivatives containing hydrazone structural units. New J. Chem. 2021, 45,4626-4631.
5. LiZhang , Xiaofen Xiao, Yuzhi Xu, Danping Chen, Jun Chen, Yingjun Ma, Zong Dai*, Xiaoyong Zou*. Electrochemical assay for continuous monitoring of dynamic DNA methylation process. Biosens. Bioelectron. 2018, 100,184-191.
6. YingjunMa, Jun Chen, DanpingChen, Yuzhi Xu, Li Zhang, Zong Dai*, Xiaoyong Zou, Short-probe-based duplex-specific nuclease signal amplifica-tion strategy enables imaging of endogenous microRNAs in living cells with ultrahigh specificity, Talanta, 2018, 186: 256-264.
7. YuzhiXu, Xiaoyu Gao, Li Zhang, Danping Chen, ZongDai*, Xiaoyong Zou,
8. Simultaneous detection of double gene-specific methylation loci based on hairpin probes tagged with electrochemical quantum dots barcodes, J.Electoranal. Chem. 2016, 781: 356-362.
9. 陈丹萍, 戴宗*, 甲基化转移酶活性的免标记电化学研究, 化学传感器, 2015, 35: 1.
10. Zhenning Yu, Si-Yang Liu, Yanfei Zhang, Yunda Li, Yuzhi Xu*, Danping Chen, Zong Dai*, Xiaoyong Zou, Pearl necklacelike strategy enables quantification of global 5-hydroxymethylcytosine and 5-formylcytosine by inductively coupled plasma-atomic emission spectrometry, Anal. Chem. 2021, 93: 7781-7791.
11.Guanglong Zhang, Zhenhua Tang, Sili Fan, Chengpeng Li, Yan Li, Weiqin Liu, Xuesha Long, Wenjing Zhang, Yi Zhang, Zhurui Li, Zhenchao Wang*, Danping Chen*, Guiping Ouyang*. Synthesis and biological assessment of indole derivatives containing penta-heterocycles scaffold as novel anticancer agents towards A549 and K562 cells. J. Enzyme Inhib. Med. Chem., 2023, 38(1): 1-15. (IF=5.75)
【专利】
1. 戴宗,陈丹萍,邹小勇,一种高通量核酸表观遗传修饰定量分析方法,CN 109182465 B (授权).
2. 戴宗,陈丹萍,邹小勇,一种Tet2序列偏好性的研究方法,CN110241175A.